My wife takes fish-oil daily as a mood stabilizer. When she skips a day or two all hell breaks lose in our house. Hell I take a smaller dose myself and it's amazing how much better I am at keeping my mood in check; I've never had much trouble but I have always gotten little edgy when hungry. That doesn't happen anymore.
In other words, even if fish-oil does work as a mood stabilizer, there would be no way for you, as a consumer of fish oil, to be even slightly certain it works.
I have no trouble believing that fish oil as a mood stabilizer can work fantastically, and yet have no physiological effect whatsoever.
1) It is a study of vitamin, mineral and essential oil supplements. There is no basis for ascribing any measured effect to essential oils as such.
2) In a number-rich report, it's odd that they don't report either the number or distribution of incidents in any detail, and I can't make their averages work out.
For example, they have 172 people in the study for an average of 142 days, and they talk about numbers like 11 and 16 incidents per thousand person-days, which would lead one to predict around 170x140x(11 to 16)/1000 ~ 250 - 300 incidents, but they then go on to talk about studying 754 Governor and minor reports, or 338 Governor reports and 416 minor reports (in all cases the reports appear to cover the full study population, which is the majority of the prison population).
One can conclude from this that most of the incidents in the prison are due to the people who weren't in the study, maybe? I don't know, but there's something odd going on.
Furthermore, they don't given any idea of individual variation within the population. The conclusion you'd draw if most of the incidents are associated with a few individuals vs spread out across the population might not be the same. Were all individuals pretty much similar in their response, or was the effect localized to some? The results as reported are consistent with a few problematic individuals becoming peaceful and everyone else getting slightly worse.
When making an argument that an intervention is good for a population, you really have to dig into the support for the claim across the population, not report averages as if they could only arise one way.
So while this is intriguing an interesting, it isn't as strongly convincing as one would like.
What I'd like to see (and would have insisted on as a reviewer) is a table showing the raw numbers of minor and Governor's reports issued on each population over the study period, and at least histograms showing the number of individuals in each populations with N Governor's and M minor reports against them, which would allow one to judge the distribution of incidents in the population.
People can't trust their own perceptions? Isn't that what gaslighting is about? Why do we accept eye-witness testimony in court cases if people should not trust their own perceptions?
If a person saw another person strike another person, should we trust their testimony? No! We should have a double-blind placebo controlled experiment where we go back in time and have a large sample size of identical people watching the same person getting struck and not struck in alternate universes and ask them if the person was struck to determine if their perceptions can be trusted.
No, you can't trust your own perceptions. You can only really trust that you are having a perception at this moment in time.
I also noticed a significantly increased blood pressure every time I took this medicine.
This continued until one day someone knocked the door just before I took my pills, and I still got the same symptoms while the pills where safely on the kitchen.
I then realised my brain had played games with me and since then the side effects disappeared.
...and I consider myself somewhat rational.
Only a "day or two?" Sounds like the placebo effect. Try swapping her fish oil capsules for something else and see if there is any difference.
This is why I take it as well. Its incredible how well it works. I hate to engage in conspiratorial thinking, but some of these overly critical analysis really seem to be coming from a big pharma "tell them the shit doesn't work" perspective. In a country with for-profit medicine, non-patented or low-profit treatments often get demonized. Especially by "useful idiots" who follow this ultra skeptical mindset where only what they hear from an authority like the government or academia, has any real value. They refuse to believe these institutions can have institutional fraud, incompetence, groupthink, or unfair motivators to getting published. As someone who works in a healthcare related field, its pretty obvious that industry controls the narrative, at least to me.
Or can be gamed by private industry and other benefactors who have a bias or agenda.
I'm wondering about that. Particularly given the increasing interest in the anti-inflammatory properties of statins & whatnot, an effective, easily obtained anti-inflammatory supplement should be very much worth looking at.
The article does not say any thing about how well tested the claimed anti-inflammatory effects of fish oil supplements are. Does anyone know?
However, I did find this gem buried quite a ways down toward the end of the article:
> Dr. JoAnn Manson, the chief of preventive medicine at Brigham and Women’s Hospital in Boston, said the large clinical trials of fish oil focused only on people who already had heart disease or were at very high risk.
If that's true, then it appears TFA is looking at it from the wrong angle. In other words, fish oils may have no effect on someone who's already suffered from a heart attack (or is at high risk), but someone who is aiming to use it as a preventative treatment might reduce their risk. Should this be the case, studying at risk populations who may have already had heart problems might not be the best starting point. It's a bit like fretting over a nutritious diet and plenty of fluids being of little use for someone who already has the flu, regardless of how poor their diet was prior.
On the other hand, jimrandomh [1] near the top of these comments links to the study and warns there may be something more at work here. This is in the thread where magic5227 points out a comment on the NYT article that the statistical work in the study raises some considerable questions because it may have established too high a burden of proof. jimrandomh's comment suggests otherwise. So, who knows. It's worth reading through that thread as well.
Personally, I think the truth is probably somewhere between these two extremes. It's apparently clear the Inuit's diet has influence on their cardiac health, but is it really just the omega-3s and not the wider range of benefits from eating fish? Or is it possibly tied to a lifetime of omega-3 intake rather than starting supplementation on a whim or only after serious health problems? If that's the case, shouldn't long-term supplementation (on the order of decades) be a focus of study instead? (Note: I have never followed fish oil studies, nor do I take it, so perhaps someone will be kind enough to link to such a study.)
Anyway, I'm no nutritionist, and I'm kind of an idiot, but it seems to me that it's the long-term dietary (or supplementation) choices we make that are most the important, hence why I am increasingly more inclined to approach studies examining short-term effects (or lack of) with caution.