As for data files, we have XMLs (yeah, I know..) over 50Mb in size.
Atom is a long way from supporting such projects. This probably doesn't apply to most web projects, but 2Mb is far from a huge file :)
SOAP dependency?
Right now, Atom is just too slow when compared with other editors such as Sublime. Given enough time it shouldn't be an issue (maybe), but right now I think it's a huge pain point for a lot of devs.
In all fairness though: I wouldn't notice 99% of the time, and I can well imagine that this problem will disappear with time.
If atom has a daemon feature that I never found, or one upcoming, I'd consider it again. Until then my workflow involves too many client closes for me to not notice the significant delay that atom has when opening a new file.
Also, for me at least, it's the principle of the thing -- we are talking about a measly few MB of text; if you can't even open that, IMO something has gone horribly wrong.
Some editors with "minimap" functionality (Sublime Text and Emacs that I'm aware of, maybe others) can give you a fairly good visual overview of large swaths of a file at once. Sometimes strange entries are obvious just because of the shape of the line and in those cases the minimap makes it easy to see when something unusual is happening.
Wait... we kind of need a text editor that can open the file, don't we?
VisualStudio handles them instantly, but even Sublime Text seems to take a bit of time "processing" it.
Snark aside, feature X is rarely absolutely needed (you can replace your generics by some boilerplate; you can use grep instead of your text editor to process huge files), but in some cases it can make your work significantly easier and that's why people want it.
In my own case, opening video files in Sublime and having the hex and ASCII side-by-side made my job significantly easier when I was writing a parser. I could easily select portions of the data (e.g. an embedded metadata), annotate it with comments from the spec, then paste it in a unit test.
I have Atom installed, but see no reason to migrating since Sublime works well enough. My only concern is that the Sublime package ecosystem will likely start rotting now that Sublime itself is essentially abandonware, so at some point I might need e.g. autocompletion for Typescript and the best package will be on Atom, not Sublime.