It's really frustrating that we can't get honest numbers on how much it takes to bring a drug to market.

In the anti-pharma camp you see people quote the manufacturing price, and then you get the pharma companies quoting their entire operating budgets.

I used to work in clinical trials, and while I cannot comment on exact figures, the drug companies pay a lot of money over a very long period to release a drug. The big problem is that they only have 3 to 5 years to make all the money back and get enough of a profit to develop more drugs. Not every clinical trial actually works out, and the courts will be a constant problem for every drug.

Do some research on the financial documents of the companies that do the clinical trials.

Doubtful, since the number would change with every single dose produced if it did.