There are a few options for scripting xfce4. You can use xfconf-query from the command line or a script. You can edit the config files in .config/xfce4. You can sync the whole .config/xfce4 directory from machine to machine - that works especially fine if all the machines run a single monitor. You can make everything repeatable using shell scripts or a configuration system like Ansible.
I use xfce but I only use xrandr (not depends on xfce) to switch between monitors and don't really know what other scripts are useful or good to have. (or what can I achieve with scripting)