Earlier betas of Mavericks were damn unstable/unusable. Apps crashing all over the place, third party apps not working because of changed APIs etc. I had to revert as well (not this beta though).
Try it in a VM first. Most things will be fine, however if it were production ready it wouldn't be marked beta. Something that you need may be disabled or in flux leaving you hanging.
which of current VMs application able to run OSX on mac hardware?
user gnufied put it best, they changed a bunch of APIs and a lot of my programs were left unworking or crashing much more than usual. With that said, I know that Mavericks was a unique use case, but still might be a good idea to wait for a few reviews.
I've usually heard the betas of OSX have been quite stable. Considering they are going to run a public beta of this I would assume it's more stable than usual OS betas they released. I was considering installing it on my main system (I only have one Mac) but you've put me off a bit. What happened to your system?