The advantage of using microspheres is that the vaccine is now monumentally safer than previous gene therapy or other vaccine attempts.
These cells begin to divide faster, and the children code for and generate the same antibody as the parent. This ups the amount of cells with that particular antibody, increasing the probability that the antigen will be targeted. They trigger inflammation to increase the flow of blood, letting more immune cells per second pass through scan the area (probably not helpful for aids, but for a cut, a splinter or a tumor that is fixed in place it is useful). They also release freestanding antibodies with the same binding profile that can disable viruses and trigger other immune cells to come slurp them up.
I think when they say they aren't taking an antibody approach they mean they aren't making an artificial antibody and just injecting it for passive immunity (sort of like injecting an immune system that can't do its own adaptation and upregulation)
The main thing with vaccines I am still confused about is what the difference between them and allergy shots is, and how do the two end up with opposite effects? I guess there is somehow a different reaction to a spike of something vs a repeated presence.
(Edit: never mind.. microspheres.. who knew?)
Those and just random magazine articles, etc. are really the only two things read/watched though, so others may know of some better options.
How does the vaccine train your immune system? My (very limited) understanding of vaccines is that you would normally train the immune system to target these weak spots by creating an antibody that would bind to said weak spot. But from elsewhere on the page, it says that the project isn't working on an antibody approach. What am I missing?