(Which goes back to one of my drums I beat here with some frequency, which is that while the rationality of humans is often overstated, so is their irrationality... many putatively irrational things like "guilt" or "empathy" in fact exist for reasons, or if you prefer, have significantly more positive effects when considered holistically than a naive analysis might indicate.)
A lot of nice things in society depend on cooperating actors not taking advantage of each other. Psychopathy is defecting on society.
(I'm not trying to be pejorative. It would be my job to prove that you're objectively wrong, and I can't.)
I think psychopathy, like all of these disorders, has a spectrum. But if it's a natural condition, it doesn't deserve the moral weight affixed to it. Not all (natural) psychopaths do bad things, and most people who do bad things are not psychopaths.