That's exactly what I'm talking about.
Would this be like living across the bay in Oakland or something? The flipside of such a situation would be that you get back home from SF at midnight before the last BART or you would have to be stuck when BART decides to strike.
Heck, when the MTA decides to strike (which is occasionally, but less frequently than BART) you can walk to Manhattan from Astoria. Try that from Oakland-to-SOMA.
All of which is to say that limiting your statement to "NYC proper" doesn't mean much because that covers a lot of ground. If you had made your orginal statement about "Manhattan south of 96th street", it would have meant what I think you were going for. Within in those parameters the East Village is middle of the pack.
Also in reference to your comment above the subways run 24/7 in NYC (albeit on a reduced schedule).