I can't stress the C++ api part of this enough. At the moment I'm building a Pascal compiler in Clojure for course work and when the time came to do byte code generation the first thing I looked to was the LLVM infrastructure both for ease of use and because it would trivially provide me with the ability to target non-x86 platforms.

The reality of the matter is that interacting with non-java linked libraries is a real pain from every JVM language know of. Two years ago this was posted here [https://github.com/jasonjckn/llvm-clojure-bindings], but since then LLVM has gone through two major restructurings so it didn't work out of the box and I estimated that it would take less effort to build my own naive infrastructure than to patch this one & integrate it.

As a result I'm generating code in terms of lists of newline terminated assembly statement strings that I can just print or write to a file when I'm done. While I agree that C is a sub-optimal output format in that you have to compile the output, it is also the clear lingua franca for systems programming and assembly generation these days. Generating C gives you interesting options like linking to other C codebases or your own C code the same way that cljs gives you the option of interacting with "native" javascript libraries as well as clojurescript toolkits.