Zotero has a desktop app in addition to their original Firefox extension. Personally, I've been very happy with it. I have my articles stored in JungleDisk, and everything syncs between mac laptop, windows desktop, and ipad (with ZotPad on the ipad).
There are plenty of reference management tools. Papers, RefWorks, Endnote, JabRef, Zotero, colwiz, readcube, and more. Here's a comparison table at wikipedia (probably not super up-to-date but worth taking a look): http://en.wikipedia.org/wiki/Comparison_of_reference_managem...
Re:Elsevier Has Bought Mendeley
by jamesjporter on Tuesday April 09, 2013 @01:21AM
(#5516565)
I've used both and found Zotero to be miles better.
[1]: http://www.zotero.org/