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Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by IAmGraydon on Friday November 13, 2026 @09:13AM (#50483786)
He honestly seems to be experiencing some level of mania, which I think a lot of people would if they were constantly in an environment that makes them believe they may have invented god. I do not think he's in his right mind. This is going to end up with a documentary about him, and not the good kind.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by illwrks on Friday November 13, 2026 @09:19AM (#50483859)
Agreed! There was a very good podcast released a few months ago, Black Box The chatbots. It’s generally about AI induced psychosis. I’d love to be a fly on the wall in some of these orgs, there’s bound to be a few people on the inside going through the same issues.

https://podcasts.apple.com/gb/podcast/black-box-the-chatbots...

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by bensyverson on Friday November 13, 2026 @09:25AM (#50483958)
I think it's just as likely VC-induced psychosis. This is what you get after 27 rounds of nonstop fundraising.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by jdb9001 on Friday November 13, 2026 @09:33AM (#50484103)
Both? Both. Both is good.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by BoxOfRain on Friday November 13, 2026 @10:27AM (#50484944)
It's been a known thing since the '60s with the 'ELIZA effect' where people misattributed personhood to a chatbot simply because it exhibited a degree of social behaviour. In my view LLMs are orders of magnitude more powerful for inducing the ELIZA effect because they mimic social behaviour and human language far more effectively. If a mere pile of S-expressions can convince someone there is a mind behind it then surely even the most sceptical of us are vulnerable to a sophisticated system directly made out of human language.

I think LLMs are an astonishingly powerful technology, but I think their tendency to induce the ELIZA effect makes it socially irresponsible to go about as though you've created a literal Deus ex machina personally.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by dgellow on Friday November 13, 2026 @09:20AM (#50483877)
If you revisit his past writing he has always been this unhinged. Took me too long, but now I see the same craziness in really a lot of what he published
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by CPLX on Friday November 13, 2026 @09:26AM (#50483968)
I still don't understand why people don't just openly talk about the obvious fact that a huge percentage of Silicon Valley leaders are on large doses of powerful stimulants.

I don't know if he is in that video or not, or ever, personally, but just in general, it's the Ockham's razor approach any time you see something like this. It's a much more direct and clear explanation than the various more convoluted theories people keep throwing around as to why everyone sounds like a methed-out megalomaniac all the time.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by somenameforme on Friday November 13, 2026 @09:31AM (#50484060)
Yeah does seem like textbook uppers.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by irthomasthomas on Friday November 13, 2026 @09:44AM (#50484255)
It certainly explains how you get the exact overlap of existential-risk fatalism and Bay Area polycule dynamics. Whos going to tell the artificial children that their parents were a high-functioning doomsday sex cult?
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by plasma_beam on Friday November 13, 2026 @09:59AM (#50484514)
As someone who has never heard or watched Dario speak before (somehow), he just comes across to me as autistic in the video.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by jacquesm on Friday November 13, 2026 @11:51AM (#50486189)
Autistic is not the word that sprang to mind.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by throwaway_7274 on Friday November 13, 2026 @10:00AM (#50484538)
The whole Bay Area is on a fatal cocktail of amphetamines, money, and neurodivergence. It's rather impolite to acknowledge, but when you take 100 people on that combination and put them in a room together, some, uh, unusual beliefs inevitably develop. Of course they do. What else would happen?
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by CPLX on Friday November 13, 2026 @10:08AM (#50484656)
Yeah exactly. And it's not the first time a highly technically proficient culture had their leaders all become amphetamine abusers with dramatic effects on world events.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by throwaway_7274 on Friday November 13, 2026 @10:41AM (#50485144)
On a bit of a rant now, please forgive me.

I never feel more like the one sober guy at the party than when I go to SF. Even when there's no reason to believe anyone is literally on drugs, it has that vibe every time. It's really unsettling. Uncanny. It starts to get under your skin, too. You start to believe, just a little bit, that everything is possible, that there are no limits, that you can and should remake the world. Just a little bit. I can never take it for more than a week at a time, no matter how beautiful the weather is. It's a relief to get back to the "real" world.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by ericbarrett on Friday November 13, 2026 @10:32AM (#50485004)
I read this comment by curuinor a while ago, and still think about it a lot. Also in response to an Anthropic story. https://news.ycombinator.com/item?id=49436647

> Look. This is a new golden age of cocaine, because of the big cuts in everything in the US took away the cocaine busting operations in Colombia and Bolivia, because the revolutionaries that previously kept control of it stood down and became a political party and new, profit-driven cartels came up, and because battery technology means that narcosubs and similar drone things work much better than before (and they can be made remote-operated, so the cops can't do shit even when they find one). Wholesale prices have halved or gone down 60% to like, 12k usd / kilo, street prices commensurate. The huge new opportunities created by increased market size have increased competition and made the cartel nature of the cartels decrease. So always think of that when you look at people acting like this and having such megalomaniac goals.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by CPLX on Friday November 13, 2026 @03:07PM (#50488937)
I hadn't heard this before. That's actually pretty interesting. My assumption has always been run-of-the-mill ADHD meds like Adderall and its several cousins, but I can't say I've got firsthand knowledge of either these days.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by IAmGraydon on Friday November 13, 2026 @12:01PM (#50486350)
We're making some big assumptions there - you may be right but who knows what's in Amodei's medicine cabinet.

That aside, I think there's something that happens to the human mind (and most people are susceptible) when exposed to certain stratospheric levels of wealth and power (which are basically the same thing). Their thinking becomes ungrounded, uncoupled from reality. The tendency is to shrug off the limitations of logic and rationality and to allow their mind to dabble in ideas of limitless possibility and power because doing so feels good to do. It's a drug and a very seductive thought that one's will could be manifested in the world without compromise - that what's inside could be made real on the outside. That is, after all, what power is. Dario's imagined reality is that he is the savior of the human race, and that's the reality he's currently living in.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by ForHackernews on Friday November 13, 2026 @10:07AM (#50484637)
https://x.com/tszzl/status/2051045196260167790

"it is a literal and useful description of anthropic that it is an organization that loves and worships claude, is run in significant part by claude, and studies and builds claude..."