Even with patents, copyrights, etc as mentioned in a sibling comment, it would be interesting what he could do if he had a fresh start. There might have been ideas that challenged the existing business that he could be free to pursue.

He'd have no shortage of talent and funding to embark on such a venture.

The big question is once the dust settles (including a possible divorce), he'll still have billions of dollars and need a reason to get out of bed. Being that he's a famous workaholic, I imagine he will try something new after he's done licking his wounds.