nonsense. you have to be very careful in designing audio software. the entire soundchain has to compute within the buffer window or you WILL get bad stuttering output. you can choose slow responsivesness or extreme optimization, and for real time performance only optimization works.

Additionally there are lookahead options in some effects that requires some delay, and clock sync for midi devices

This isn't mutual exclusive to my statement, so, please don't be so offensive and call it nonsense.