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Re:Ozempic-style drugs now in trials for heart failure, addi... by Melatonic on Saturday November 07, 2026 @01:31AM (#50402181)
What naturally is supposed to produce GLP-1 in our bodies ?
Re:Ozempic-style drugs now in trials for heart failure, addi... by zemoerfi on Saturday November 07, 2026 @02:21AM (#50402405)
It's important to remember that the natural GLP 1 you produce is a very very different molecule than GLP 1 agonists. The body uses natural GLP 1 in minutes. These drugs attach a very complex molecule to the GLP 1 site, allowing it to stay active there for hours.

So while your body produces it in a few places, the product gets used up almost immediately.

Re:Ozempic-style drugs now in trials for heart failure, addi... by shawa_a_a on Saturday November 07, 2026 @06:39AM (#50403663)
Keeping that in mind then, what processes do produce the (short lived) GLP 1?
Re:Ozempic-style drugs now in trials for heart failure, addi... by zemoerfi on Saturday November 07, 2026 @09:31AM (#50404858)
It is produced naturally by the intestine and brain stem when food is present. It happens in response to fats, proteins, and carbs.
Re:Ozempic-style drugs now in trials for heart failure, addi... by thebigspacefuck on Saturday November 07, 2026 @08:51AM (#50404521)
Re:Ozempic-style drugs now in trials for heart failure, addi... by jkahrs595 on Saturday November 07, 2026 @10:20AM (#50405293)
That link is great, but putting jelly beans above peanuts makes zero sense to me, anecdotally. I can’t argue with the numbers/science but peanuts are something I reach for often when I’m looking to feel full, they are really great for that.