Re:Ozempic-style drugs now in trials for heart failure, addi...
by seanmcdirmid on Friday November 06, 2026 @11:23PM
(#50401592)
Ya, you are still ramping and the smaller doses are to see if there will be problems before you hit 30mg. You should notice something when you hit 10mg though.
Re:Ozempic-style drugs now in trials for heart failure, addi...
by gruturo on Saturday November 07, 2026 @06:18AM
(#50403546)
30mg is an extremely high dosage, far beyond the maximum Semaglutide (Wegovy) trials (which initially topped out at 2.4 and years later validated a new max of 7.2) and likely to land you in a hospital.
Even 10mg is very, very high, beyond the trials maximums (though preliminary small escalation trials tested that, even reaching 16mg, I guess the participants really didn’t enjoy that) and would have serious side effects if not result in a hospital visit as well.
Please be a lot more careful dispensing advice on a public forum on matters where people could get hurt.
Re:Ozempic-style drugs now in trials for heart failure, addi...
by iand on Saturday November 07, 2026 @07:10AM
(#50403852)
Oral Wegovy is dispensed in higher doses than injection presumably because uptake via the gut is lower.
Re:Ozempic-style drugs now in trials for heart failure, addi...
by JKCalhoun on Saturday November 07, 2026 @09:47AM
(#50405007)
Yeah, came here to say you can't compare dosages across drugs—they are in some cases an order of magnitude different.
Re:Ozempic-style drugs now in trials for heart failure, addi...
by seanmcdirmid on Saturday November 07, 2026 @03:40PM
(#50407834)
I misremembered the dosage, it’s 25 mg, not 30 mg. It’s pretty standard for oral, since absorption is different from injection.
I'm assuming this is normal and something will happen when I up the dose.