Ozempic-style drugs now in trials for heart failure, addiction and even aging

Re:Ozempic-style drugs now in trials for heart failure, addi... by Sohcahtoa82 on Friday November 06, 2026 @05:53PM (#50399590)

I'm not the GP, but I can answer this.

I did try keto before. Heavy protein, low carbs. Everyone promised a high protein/fat/fiber diet with low starch/sugar was the secret to feeling full sooner and for longer.

Nope. Didn't change a damn thing. I was still hungry all the time.

My experience mirrors the GP. Ozempic really flipped the switch. See my other comment (https://news.ycombinator.com/item?id=50399564) for more.

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Re:Ozempic-style drugs now in trials for heart failure, addi... by gib444 on Saturday November 07, 2026 @03:56AM (#50402853)

[delayed]

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Re:Ozempic-style drugs now in trials for heart failure, addi... by i2amsam on Saturday November 07, 2026 @09:28AM (#50404845)

I’ll add, I did keto and found I lost weight and was relatively able to control hunger, but my food choices were very narrow and everything needed careful planning, additionally my cholesterol and blood lipids went up a concerning amount, enough that my doctor recommended medication.

On a glp I don’t need to carefully plan my diet because carb-heavy or greasy foods are unappealing to consider. It’s a very strange feeling for me to look at a big menu and realize I want to order the salad, not that I “should”, and my cholesterol levels fell by 66%

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Re:Ozempic-style drugs now in trials for heart failure, addi... by GeoAtreides on Saturday November 07, 2026 @12:20PM (#50406238)

I'm going to say something brave and controversial (/s), and I'll accept the downvotes and flagging: I don't believe you. I don't believe keto (or keto-ish) didn't lead to lower hunger cravings. Maybe you're missing some things from your story? maybe you're misremembering some things?

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