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Re:The brain may be about to have its Ozempic moment by odo1242 on Tuesday August 11, 2026 @04:50PM (#49264281)
Caffeine doesn't actually do any of the things sleep does to your brain. If you drink coffee during a late night, you won't feel as tired, but your brain performs worse, your reflexes are slower, you're less likely to remember things, etc. It's like painting over a rusted car instead of properly maintaining it, basically.
Re:The brain may be about to have its Ozempic moment by binary132 on Tuesday August 11, 2026 @05:02PM (#49264433)
I think GP was just making a point about the fact that “tired” is a subjective experience, like pain. Arguably, if you’re on pain medication, you’re not in pain, even if your body is sending pain signals that your brain just isn’t receiving or paying attention to.
Re:The brain may be about to have its Ozempic moment by Gooblebrai on Tuesday August 11, 2026 @05:22PM (#49264688)
Indeed. Pain is also interesting because chronic pain, AFAIK is sometimes a misfiring of pain signals even when nothing is physically wrong.

Turning off that misfiring with drugs would be dangerous (pain is an alert) but also improve the quality of life of so many people!