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A comment on The first early human eggs from stem cells. Parent comment

Re:The first early human eggs from stem cells by scotty79 on Wednesday July 01, 2026 @02:47AM (#48743105)
Can you point me to anything about mitochondrial transplants? I'd love to see bat mitochondria transplanted into other mammals. They must have really superior ones given the energy expenditures needed to support flight and their long lifespans.
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Re:The first early human eggs from stem cells by Protostome on Wednesday July 01, 2026 @02:55AM (#48743154)
I will let the experts continue from here :) This review is from 2020, i bet things have progressed since then

https://pmc.ncbi.nlm.nih.gov/articles/PMC7169912/

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Re:The first early human eggs from stem cells by scotty79 on Wednesday July 01, 2026 @06:18AM (#48744600)
It's not so much a mitochondrial transplant, as it is fertilized egg nucleus transplant. Not just mitochondria are used from the third donor but their whole egg (sans nucleus). So unless a human might develop from a bat egg just from swapping out nucleus, which I'm sure it's not the case, super-powered batman must remain a fantasy.
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Re:The first early human eggs from stem cells by Protostome on Wednesday July 01, 2026 @06:53AM (#48744829)
Oh, so that's what you were aiming for, LOL

there are many reasons for this chimera not to be viable, mitochondria co-evolves with the nuclear DNA, you can't just take a mitochondria from a totally different species

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Re:The first early human eggs from stem cells by scotty79 on Wednesday July 01, 2026 @09:19AM (#48746289)
Bats are kinda close though. Maybe it would require just a handfuls specific adjustments to nuclear DNA, at most. Worth a shot if it could give us for example 2x multiplier for a healthy lifespan. Even getting 10 year old mice would be very cool.
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Re:The first early human eggs from stem cells by type0 on Wednesday July 01, 2026 @03:30AM (#48743385)
I don't, isn't this the recipe to get IRL Morbius?
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Re:The first early human eggs from stem cells by NoGravitas on Wednesday July 01, 2026 @09:24AM (#48746359)
Or Man-Bat.

https://en.wikipedia.org/wiki/Man-Bat

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Re:The first early human eggs from stem cells by Schlagbohrer on Wednesday July 01, 2026 @03:21AM (#48743325)
Batboy, real at last
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