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A comment on GLP-1 drugs led to weight loss and reversed depression-like behavior in mice. Parent comment

Re:GLP-1 drugs led to weight loss and reversed depression-li... by amanaplanacanal on Sunday June 28, 2026 @06:10AM (#48705998)
I don't think I could do it, but 3.5 cups of peanut butter would get you there. Or four 16 ounce ribeyes.
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Re:GLP-1 drugs led to weight loss and reversed depression-li... by s1artibartfast on Sunday June 28, 2026 @04:30PM (#48711310)
It doesnt have to be one sitting. Eat 2500 diet and add a cup of roast nuts twice a day and you are basically there.

Moreover, you dont need to eat anywhere close to 5k to be morbidly obese.

1 cup of roast nuts over TDEE will gain you 100lbs in a couple short years

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Re:GLP-1 drugs led to weight loss and reversed depression-li... by faangguyindia on Monday June 29, 2026 @01:16PM (#48722049)
Assuming you maintain same activity level, the increase in weight wouldn't be that simple.

TDEE rises as body weight rises (heavier body burns more)

Overfeeding increases NEAT in some people (more fidgeting, movement)

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Re:GLP-1 drugs led to weight loss and reversed depression-li... by s1artibartfast on Tuesday June 30, 2026 @03:26PM (#48737998)
I cup over TDEE will always be more as it raises
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