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A comment on GLP-1 drugs led to weight loss and reversed depression-like behavior in mice. Parent comment

Re:GLP-1 drugs led to weight loss and reversed depression-li... by faangguyindia on Monday June 29, 2026 @01:16PM (#48722049)
Assuming you maintain same activity level, the increase in weight wouldn't be that simple.

TDEE rises as body weight rises (heavier body burns more)

Overfeeding increases NEAT in some people (more fidgeting, movement)

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Re:GLP-1 drugs led to weight loss and reversed depression-li... by s1artibartfast on Tuesday June 30, 2026 @03:26PM (#48737998)
I cup over TDEE will always be more as it raises
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