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Re:GLP-1 drugs led to weight loss and reversed depression-li... by shlant on Sunday June 28, 2026 @03:59AM (#48705330)
supposedly that comes mostly from observational studies whereas RCT's seem to show that at some point full regain will probably happen (although can take 1-2 years). The Observational studies don't seem to control for people stopping GLP-1's but still trying other drugs/weight loss methods which is where the discrepancy from RCT's seems to be.
Re:GLP-1 drugs led to weight loss and reversed depression-li... by JumpCrisscross on Sunday June 28, 2026 @09:21AM (#48707050)
> supposedly that comes mostly from observational studies whereas RCT's seem to show that at some point full regain will probably happen

Do you have one you’d recommend reading?