Are they hiding true solutions treating the underlying issues?

Consider history, the incentives, and the current political climate.

I don't think they are hiding true solutions but they are not pursuing them.

Their R&D is directed at treating common chronic conditions with drugs that you have to take forever. That's what makes them money. Treatments for rare conditions or true solutions do not. It's just economic motivation.

That's also why when they do develop something for a rare condition, it costs a bankrupting amount of money.

A researcher who discovered a "true solution" would be fired or assassinated or discredited via propaganda to utter irrelevance. Too many incoming billions at risk.

Pharma companies don't control the availability of calories

And anyway, demonstrably not true given that pharma companies are working on a number of drugs that are one-and-done treatments for things like Lp(a). We should figure out a way to make them fabulously wealthy for achieving breakthroughs like that even without a lifetime prescription.