News for hackers. Stuff that matters.
Re:Copper transport drug restores memory and clears toxic Al... by kurthr on Monday June 15, 2026 @05:16PM (#48547123)
Wow, it sure didn't take long to show a complete lack of familiarity in the field. It seems like that's going to be a real weakness with LLMs based on volumes of material that are later discovered to be semi-fraudulent and unmotivated by scientific principals.

https://stanforddaily.com/2023/12/31/blockbuster-alzheimers-...

Re:Copper transport drug restores memory and clears toxic Al... by DavidSJ on Monday June 15, 2026 @05:37PM (#48547341)
As noted elsewhere in this thread, which you seem not to have read, I discuss that matter in the article, which you also seem not to have read.
Re:Copper transport drug restores memory and clears toxic Al... by kurthr on Monday June 15, 2026 @10:30PM (#48549817)
Not only have I read it, I know people mentioned in it. There aren't very many.
Re:Copper transport drug restores memory and clears toxic Al... by DavidSJ on Tuesday June 16, 2026 @02:28AM (#48551334)
You read the article in which I discuss the matter you say I was unfamiliar with?
Re:Copper transport drug restores memory and clears toxic Al... by thechao on Tuesday June 16, 2026 @08:21AM (#48554095)
I'm responding to a random comment: I was in molecular biology, but >20 years ago. Your article immediately presents as someone who's acquired reading expertise in a biological/medical subfield. Second, your initial survey presents as a "brittle x": AB is the proximal cause all by itself; but, it can also be the secondary cause from many vectors. Diseases like that are (essentially) impossible to explain to the public. Also, the biological principle function is a standard trope for "good for X in the short run, bad for the person in the long run".
Re:Copper transport drug restores memory and clears toxic Al... by DavidSJ on Tuesday June 16, 2026 @09:44AM (#48555226)
Thanks for these comments! The multiple pathways into a common entrypoint is definitely a challenge to communicate.
Re:Copper transport drug restores memory and clears toxic Al... by ncr100 on Tuesday June 16, 2026 @10:28AM (#48555873)
This form of hostile challenge is discouraged in the HN rules:

https://news.ycombinator.com/newsguidelines.html

Re:Copper transport drug restores memory and clears toxic Al... by DavidSJ on Tuesday June 16, 2026 @02:16PM (#48559578)
That's fair. I responded to hostility with hostility. Perhaps I should have ignored the comment or just responded kindly despite the hostility.