Re:The Ballad of TIGIT
by choilive on Tuesday May 26, 2026 @09:31PM
(#48288335)
Everything is obvious in hindsight, but the data (and theory) at the time was that this had a really good shot at being the next big thing in a world where >90% of drugs never make it past clinical trials. 10% probability of success * $200B in lifetime sales (assuming a Keytruda level smash hit) means an EV of ~$20B or more. Not a surprise more than a few companies wanted a shot at it.
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Re:The Ballad of TIGIT
by doctorpangloss on Tuesday May 26, 2026 @09:49PM
(#48288464)
Actually a lot of drugs make it all the way through to approval from Phase I. I think you probably mean preclinical to approval. It's something like 33% across all therapy areas in the USA, and in some areas closer to 50%.