There is also UMU Launcher[0] which is basically all that without the Steam integration/dependencies so you can run games from GOG and other stores (it is a command-line tool but launchers like Heroic can use it behind the scenes). I used to install dxvk, etc manually but in recent months i switched to it as it tends to work much more seamlessly for games (i did disable its autoupdates though).

[0] https://github.com/Open-Wine-Components/umu-launcher