Is that comment trying to be intentionally dense? They're talking about E123 & co, synthetic ones.

"E123 & co" are descriptors covering both "organic" and "synthetic" substances, because their role is to add precision and clarity to an engineering process, not entertain the pseudoscientific naturalistic bullshit masses buy into (which by itself is just a way for another industry to make money - or do you think people come up with those fitness/healthy eating fads all on their own?).