CloneDrive shouldn't be needed anymore, since Windows 8 (finally) has built-in support for mounting ISO images.
The point of my comment was a weakness in Windows 8 beyond mountins ISOs
I've been using Virtual CloneDrive on Win 8 RTM since the first day I upgraded my computers (about 2 months ago), because I had to re-install several softwares from iso's... It worked just fine, and I actually never suspected any incompatibility issues.
Beyond that, we were developing interception technologies to hook inside windows 8 metro applications successfully.