Vitamin D and Omega-3 have a larger effect on depression than antidepressants

Re:Vitamin D and Omega-3 have a larger effect on depression ... by andruby on Thursday January 29, 2026 @08:54AM (#46810211)

> The truth about antidepressants is that the majority of people with depression that respond to an antidepressant would also have responded to a placebo.

^ citation needed

What does "would have responded" mean? Are you saying that >50% of people with depression that are "helped" by antidepressant, would have been helped _to a similar extend_ with a placebo?

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Re:Vitamin D and Omega-3 have a larger effect on depression ... by arghwhat on Thursday January 29, 2026 @09:15AM (#46810481)

I believe that is indeed what they meant. The perception of being given a remedy is very powerful indeed, especially for issues ultimately linked to the mind.

That placebos can work should not be seen as undermining the severity or pain of the depression, but rather underline the power of tricking the mind into improvement.

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Re:Vitamin D and Omega-3 have a larger effect on depression ... by Murfalo on Thursday January 29, 2026 @06:44PM (#46818553)

Two papers that might be of interest to people regarding this topic would be Kirsch 2014 and Cipriani 2018.

And yes, agreed with argwhat.

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