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A comment on From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency. Parent comment

Re:From blood sugar to brain relief: GLP-1 therapy slashes m... by michaelbuckbee on Wednesday November 26, 2025 @12:59PM (#46060389)
I agree with you. All I can think is that it's affecting some central mental or physical aspect that has many different outward benefits.
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Re:From blood sugar to brain relief: GLP-1 therapy slashes m... by toomuchtodo on Wednesday November 26, 2025 @01:52PM (#46061006)
It patches the reward center in the brain, which improves everything downstream of that (as mentioned in llm_nerd's sibling comment to yours).

https://news.ycombinator.com/item?id=45907422 (citations)

(i am hopefully that probiotics might be a future path to curating gut microbiota that meets an individual's GLP-1 in vivo production needs based on target metabolic outcome, but immediate intervention is welcome for obvious health reasons at scale)

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