Still, it would make a bit of sense if you can find a place in your code where crossing a region hurts less, to move some of your services to a different region.
While your business partners will understand that you’re down while they’re down, will your customers? You called yesterday to say their order was ready, and now they can’t pick it up?
But there are some people on Reddit who think we are all wrong but won't say anything more. So... whatever.
Nothing in the outage history really stands out as "this is the first time we tried this and oops" except for us-east-1.
It's always possible for things to succeed at a smaller scale and fail at full scale, but again none of them really stand out as that to me. Or at least, not any in the last ten years. I'm allowing that anything older than that is on the far side of substantial process changes and isn't representative anymore.