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Re:Tiny Microbe Challenges the Definition of Cellular Life by adrian_b on Wednesday August 20, 2025 @02:14AM (#44959138)
In my opinion, a virus in the environment is quasi-dead, but once it enters a cell and it hijacks its components, it becomes alive.

This does not differ that much from bacterial or fungal spores, or even from plant seeds, which can also be almost "dead", i.e. without detectable metabolism or internal changes, even over many thousands of years, until they reach a favorable environment that triggers their revival.

The difference between a virus and a bacterial spore is that the viral particle contains only a subset of the parts of a living organism, so it could never be brought back to life in an environment where nothing is already alive. However, once the virus takes control over many parts of a cell, which provide the functions that it is missing, like the machinery for protein synthesis, the ensemble formed by the parts brought by the viral particle and the parts formerly belonging to the invaded cell, can be considered as alive and distinct from what the invaded cell was previously.

In any case, the evolution of the viruses and the evolution of the cellular forms of life are entangled, with a lot of genetic material exchanged between them, so considering the viruses as non-living is definitely counter-productive, because neither the viruses nor the cellular forms of life can be understood separately.

Re:Tiny Microbe Challenges the Definition of Cellular Life by djmips on Wednesday August 20, 2025 @03:38AM (#44959609)
That's a pretty cool framework for the alive or dead debate. I've always been firmly on the alive side but now I can do a better job of presenting the argument concretely instead of just ' nuh-uh '
Re:Tiny Microbe Challenges the Definition of Cellular Life by close04 on Wednesday August 20, 2025 @05:27AM (#44960233)
> so it could never be brought back to life in an environment where nothing is already alive

I always thought of a virus as purely a "modifier", not having the characteristics of "life" independently. If this was a game, the virus might be a runestone or skin for your character.

Anything that doesn't need external "life" to come alive, I would consider as "life" in various states. Maybe it's in hibernation, or stasis, or dormant but the life is there. Maybe to keep the silly game analogy, this might be the extra character on your roster.

Re:Tiny Microbe Challenges the Definition of Cellular Life by klez on Wednesday August 20, 2025 @06:01AM (#44960440)
> Anything that doesn't need external "life" to come alive, I would consider as "life" in various states

Doesn't almost any biological entity need external life to come alive via, e.g. reproduction or mitosis or what have you?

Re:Tiny Microbe Challenges the Definition of Cellular Life by close04 on Wednesday August 20, 2025 @07:21AM (#44960822)
Yes but you are talking about the threshold of existence, and the cell is alive as soon as it starts existing. For a virus you also have the threshold of "application", when the viral code is applied to something alive. Before that the virus exists but is not alive itself. After the application it's modifying other life which maybe technically can be considered alive.

This is why I said "to come alive" instead of "to be created". The virus is something that just exists but only becomes alive when mixed with something that's already alive.

Re:Tiny Microbe Challenges the Definition of Cellular Life by eru on Wednesday August 20, 2025 @06:29AM (#44960581)
The virus behaves a bit like the seed of certain plants (like many orchids) that need obligatory symbionts. The seed by itself is not viable.
Re:Tiny Microbe Challenges the Definition of Cellular Life by Ultimatt on Wednesday August 20, 2025 @09:19AM (#44961701)
The word you're looking for is cryptobiosis/anabiosis no need to invent a new one. Something thats later alive almost by definition is not dead. The entire living system has been alive since abiogenesis.
Re:Tiny Microbe Challenges the Definition of Cellular Life by IAmBroom on Wednesday August 20, 2025 @11:37AM (#44962917)
We have to agree on the basic definition of ultra-basic terms.

You just proposed a definition. Good. It's not complete, but necessary, conditionally.

Basically, we shouldn't use "alive" and "dead" as dualities. There's at least three states: "dead/inert/never gonna get there", "meets a definition of life (see next category) when supplemented by a host cell or something else complex and exterior", "can self-replicate and grow on its own, in a friendly environment with sufficient food/fuel/inputs available = life".

Maybe more. But let's stop pretending biology is dead versus alive, because viruses definitely ruin that.

Re:Tiny Microbe Challenges the Definition of Cellular Life by mabster on Wednesday August 20, 2025 @07:14PM (#44967491)
"Alive / dead / iffy" still seems to hold up.
Re:Tiny Microbe Challenges the Definition of Cellular Life by mwigdahl on Wednesday August 20, 2025 @11:54AM (#44963055)
That is not dead which can eternal lie...