Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol...
by astrange on Wednesday August 06, 2025 @02:51AM
(#44808541)
Fun fact: eating a bunch of black pepper cancels that out.
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Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol...
by ggsp on Wednesday August 06, 2025 @04:20AM
(#44809234)
This spiked my interest, so I looked around and found a 2018 paper (DOI: 10.1039/c7fo01715d) which, when fed into an LLM, gave me the following information (edited for brevity and clarity). Please note that I did not verify any of the LLM's claims, so take with a pinch of salt. Or pepper.
The study tested a black pepper-based beverage (BPB) containing 20 mg gallic acid equivalent of polyphenols.
Key findings:
- Lowered hunger by 17%
- Reduced desire to eat by 15%
- Decreased prospective food consumption by 17%
- Increased satiety by 14%
- Increased fullness by 16%
What didn't change:
- Blood glucose and insulin responses
- Gastrointestinal discomfort
- Gut hormones (PYY and GLP-1)
Approach:
- The beverage was consumed 10 minutes before a meal
- It contained water-extracted black pepper compounds (not piperine, which isn't water-soluble)
- The extraction used hot water at 90°C for 3 minutes
If you want to try this:
1. Make a black pepper extract: Steep 20g of black pepper in 100ml of hot water (90°C) for 3 minutes, then strain and dilute with 900ml of water
2. Timing: Consume about 10-15 minutes before meals
3. Monitor your response: Track your appetite sensations to see if it works for you
Critical notes:
- The appetite-suppressing effects appear to be from water-soluble polyphenols (like apigenin and luteolin compounds), not piperine
- The study was short-term, so long-term effects are unknown
- Individual responses may vary
- This won't affect your blood sugar or metabolism directly
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol...
by astrange on Wednesday August 06, 2025 @06:10AM
(#44810079)
I meant it cancels out the effect of THC. Which is handy if you've taken an edible and are getting tired of it. But yes, that too.
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol...
by ggsp on Wednesday August 06, 2025 @10:42AM
(#44812679)
Oh, now I get it, you're saying that the black pepper "unhighs" you? Never knew that, I'm going to have to try that sometime. Do you just munch on a teaspoon of peppercorns?
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol...
by astrange on Wednesday August 06, 2025 @07:51PM
(#44819202)
Yep.
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol...
by JumpCrisscross on Wednesday August 06, 2025 @09:20AM
(#44811614)
> when fed into an LLM, gave me the following information (edited for brevity and clarity). Please note that I did not verify any of the LLM's claims
Please don’t do this.