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Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by Aurornis on Tuesday August 05, 2025 @04:03PM (#44803520)
> And also the idea that it is "easy" to lose weight is completely out of touch. If it was there wouldn't be millions of people trying hard, spending money on trying and failing for decades, and entire businesses addressing that.

This is a touchy topic, but I would like to point out that you're missing the obvious confirmation bias that comes with this observation.

There are many people who modulate their weight by changing what they eat, how much they eat, reducing snacking, meal planning, and changing their shopping habits.

You don't see them among the millions of people failing to lose weight or paying for expensive solutions because they quietly solve their problem.

I'm also not suggesting it's easy, but we should acknowledge that many people do successfully control and modulate their weight through dietary and habit changes. There's a survivorship bias problem that occurs when you only look at the remaining sub-group who has the most difficulty with this.

Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by cm2187 on Tuesday August 05, 2025 @05:05PM (#44804284)
and there are people who don't get fat no matter what they eat. Not sure what difference it makes to the millions of people I am refering to. Not even sure what is your point.
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by Aurornis on Tuesday August 05, 2025 @08:14PM (#44806135)
> and there are people who don't get fat no matter what they eat.

This is a myth.

When you actually track what these people eat, their daily caloric intake averages out to numbers you'd expect. At best, the difference between "fast metabolism" and "slow metabolism" people in studies comes out to a couple hundred calories per day.

You may witness someone consume 2 pizzas and a soda in one sitting without getting fat, but that person is consuming fewer calories for the rest of the day or the week to offset it.

Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by cortesoft on Tuesday August 05, 2025 @11:39PM (#44807351)
I think what they mean is "they eat whatever they want and however much they want" and still don't get fat.

Some people just only want to eat an amount that doesn't get them fat. They aren't using any willpower or anything, they just don't want to eat more than a healthy amount for them.

I am not one of those people (I am overweight when I eat as much as I want), but I am for other things. For example, I don't drink very often (only maybe 10 times a year) and don't get very drunk when I do. I just don't feel a desire to drink very often. It takes zero self discipline to not drink for an extended period of time because I don't have the desire for it.

On the other hand, many alcoholics struggle mightily to avoid drinking. It takes all their willpower to not drink.

Everyone is different in their ability to avoid different addictions.

Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by sfn42 on Wednesday August 06, 2025 @05:57AM (#44809978)
I feel like the word metabolism is often misunderstood. My metabolism is just the number of calories I need to maintain my weight. If I start being more active my metabolism increases, if I become less active it decreases.

So, metabolism is really just an expression of how active we are. Some athletes eat 5-10,000 calories a day just to maintain their weight. Hard working laborers also need a lot more calories than office workers.

Meanwhile, people blame their metabolism as if it's just a trait they can't control like their height. You absolutely can increase your metabolism, just move more. This is also likely a big reason why many people gain weight in adulthood - in school we have weekly gym classes and we spend lots of time running around ad playing with friends etc. Then we grow up and our activity level plummets, but we don't adjust our diet to accommodate our much lower metabolism.

Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by XorNot on Tuesday August 05, 2025 @05:26PM (#44804552)
With 40% of US adults overweight, that is a substantial plurality though. It's not confirmation bias when it's more then 1 in every 3 people.
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by Aurornis on Tuesday August 05, 2025 @08:17PM (#44806158)
> It's not confirmation bias when it's more then 1 in every 3 people

If you construct your argument to exclude the 2 out of 3 people who are not overweight and then point out that the remaining 1/3 is overweight, that's the definition of confirmation bias.

It's also a disingenuous argument because not all of those 40% are actively trying and failing to modulate their weight in any way. Most people just don't care.

Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by Der_Einzige on Tuesday August 05, 2025 @11:42PM (#44807366)
No way that it’s only 40%. Well over half are overweight. Any definition claiming only 40% is lumping in a lot of fatties with the “not overweight”.
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by Izkata on Wednesday August 06, 2025 @01:05AM (#44807879)
They got the right number with the wrong descriptor. It's about 40% obese (and 78% overweight, last I remember).
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by throwup238 on Wednesday August 06, 2025 @02:58AM (#44808593)
> I'm also not suggesting it's easy, but we should acknowledge that many people do successfully control and modulate their weight through dietary and habit changes.

For example: weightlifters. It’s standard operating procedure to “bulk up” - periods where lifters overeat to promote muscle growth - and then diet to “cut” weight to drop the fat gained during the bulking period while keeping the muscle. They tend to be extremely motivated individuals though.

Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by RivieraKid on Wednesday August 06, 2025 @05:39AM (#44809865)
The selection bias also works for genetics. For me, it's basically impossible to become fat.