Re:Sleep all comes down to the mitochondria
by crocowhile on Wednesday July 30, 2025 @09:12AM
(#44733768)
It is an awful paper and I am a very expert in this area. This is science, alas.
Re:Sleep all comes down to the mitochondria
by kridsdale1 on Wednesday July 30, 2025 @12:16PM
(#44736152)
Please elaborate.
Re:Sleep all comes down to the mitochondria
by crocowhile on Thursday July 31, 2025 @01:39AM
(#44742630)
The conclusions are pushed and hyperbolic exactly to get this type of reaction from the public, at best conflating control with function (we solved sleep) while the sleep phenotype itself is basically non-existing.
Proper rebuttals will come up in due time on the appropriate channels. all the colleagues I talked to are as pissed off as I am about this way of doing science.
Re:Sleep all comes down to the mitochondria
by flobosg on Thursday July 31, 2025 @01:09PM
(#44747722)
“They hyped their conclusions a lot” is par of the course, but
> the sleep phenotype itself is basically non-existing
is not. Can you explain that in more detail?
Re:Sleep all comes down to the mitochondria
by flobosg on Wednesday July 30, 2025 @09:21AM
(#44733865)
Not an expert, but I’d love to hear more about what makes it awful.
Huh, you actually are an expert in this area. I’m curious to hear more too.
> There, I studied the early stages of neuronal development in the Drosophila embryo… > I graduated with my Ph.D. in September 2006 and decided that I would continue my research activity on sleep, using flies as the animal model.
Re:Sleep all comes down to the mitochondria
by Tokumei-no-hito on Wednesday July 30, 2025 @10:28PM
(#44741786)
you are arguably the most educated expert on the subject available on HN. any chance you will share your thoughts on here, your blog or mastodon?
https://www.nature.com/articles/s41586-025-09261-y
Not an expert in this area, but the essay feels a bit like an oversimplification. Not only is this in flies, but I wasn't entirely convinced this isn't about rest rather than sleep per se. It's a cool paper, interesting to read and read about, but my hunch is there's more steps in the chain, and am not sure it will replicate in humans or even mammals. But maybe I'll be wrong.