Evolution directly challenges the idea that humans are very special creatures in a universe where mighty mystic forces care about them a lot.
Climate changes, and the weight of human industry in it, challenges directly the life style expectations of the wealthiests.
Some of neurology/psychology gets a bit closer, but science of the brain doesn't have major theories that are taught on the same level nor have much impact on public policy. The closest I can think of is how much public awareness of what constitutes a mental disorder lags behind science, but that area is still constantly contested even among the researchers themselves and thus prevents a unified message being given to the public that they must then respond to (choosing to believe the science or not).
Hey, weren't we just talking about propaganda?