Maybe in the first few weeks, but their half-life is 7 days. You're not doing much besides making a hassle for yourself if your doing that after the first couple of weeks

The amount of "time on" is completely irrelevant. You will reduce peaks and troughs by injecting > once/week, this is a fact.

Yeah, I guess it's worth adding my relatively moderate side effect experience has been dosing 2-3x/week the whole time.