There's a few, but they're large, expensive, require a lot of electricity and have limited range; there's the Silent Hunter [0] which is 30-100 kilowatts max power but which has a range of up to 4 kilometers. Raytheon has a 10 kilowatt palletized version that can go on a truck bed [1]; I can't find any numbers but it's listed as short-range, so I presume it's only effective at distances of less than 1 km, probably only tens or hundreds of meters. Plus they need to detect the drones first, but there's multiple ways to do that. It likely needs a network of detectors though.

[0] https://en.wikipedia.org/wiki/Silent_Hunter_(laser_weapon)

[1] https://www.rtx.com/raytheon/what-we-do/integrated-air-and-m...