News for hackers. Stuff that matters.

A comment on Adipose tissue retains an epigenetic memory of obesity after weight loss. Parent comment

Re:Adipose tissue retains an epigenetic memory of obesity af... by Aurornis on Thursday April 17, 2025 @12:11PM (#43718868)
Yeah, it's well known that steroids shut you down. The problem with the broscience is that the PCT is talked about like it reverses everything like an antidote, but long-term bodybuilders often end up on TRT because eventually they can't get back to baseline.
[ Parent | on HN ]
Re:Adipose tissue retains an epigenetic memory of obesity af... by gr3ml1n on Thursday April 17, 2025 @03:35PM (#43721169)
That isn't true. Dedicated bodybuilders, starting more commonly ~5 years ago, decided that PCT wasn't worth it. Instead of typical 16-20 week cycles followed by 4-6 weeks of PCT, they adjust the dose between supraphysiological and (generally) top-of-normal, i.e.: blast and cruise.

It's not because they couldn't recover, it's because they don't want to or see the point.

[ Parent | on HN ]