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Re:Adipose tissue retains an epigenetic memory of obesity af... by sleepyguy on Thursday April 17, 2025 @11:06AM (#43717997)
It seems fasting causes Adipocyte apoptosis. It makes sense, there is cell death.

I lost 100 lbs fasting over 1.5 years. I did gain some weight back after stopping, but not much. Strangely, where I saw fat return was not where most of it came off.

Re:Adipose tissue retains an epigenetic memory of obesity af... by meindnoch on Thursday April 17, 2025 @02:43PM (#43720643)
Yeah, but fasting is extremely unpleasant.
Re:Adipose tissue retains an epigenetic memory of obesity af... by sleepyguy on Thursday April 17, 2025 @06:09PM (#43722761)
You get to know yourself well after about 5 days of zero food..... :))
Re:Adipose tissue retains an epigenetic memory of obesity af... by MrGilbert on Friday April 18, 2025 @01:29AM (#43725286)
I did that, and it helped to kickstart further weightloss. I was surprised how fast my body got rid of stored water, and how quickly I lost fat in the upper body region, primarily around my face, neck and shoulder.
Re:Adipose tissue retains an epigenetic memory of obesity af... by 542354234235 on Friday April 18, 2025 @11:08AM (#43728787)
Even much shorter fasts help you to understand how unimportant and fleeting a lot of feelings of hunger are. You get hunger pangs and feel like you need to eat, but in a hour it has passed and you go another 8+ hours just fine. When I eat some crappy food, I know it is going to make me feel very hungry in a few hours, but when it happens, I know it isn’t a real need and it helps stop the cycle of bad eating/overeating.
Re:Adipose tissue retains an epigenetic memory of obesity af... by BigGreenJorts on Saturday April 19, 2025 @04:23PM (#43739196)
I'm not religious at all, but I still sometimes practice Ramadan for this reason. On top of the communal experiences of charity and shared meals that are more present during the month, the reminder that my body is greedy for food and does not really need so much is such a good annual reminder to have.
Re:Adipose tissue retains an epigenetic memory of obesity af... by mapkkk on Tuesday April 22, 2025 @02:44AM (#43759628)
I'd love to hear more about your experience! How you went about it, what (if anything) did you do to prepare, if it was hard or easy, or if you have any tips or any specific thing about the experience you think would be beneficial to mention.

If you have the time, I would really appreciate it if you reached out to me. You can find my contact info on my profile page, there's also a link to an anonymous contact form, if you'd prefer that. Thank you!