I'm willing to assume I'm non typical, but I definitely had temporary nerve pain effects from a B-complex supplement; I can't remember if I noticed that after the first night or the second; my spouse reported nothing like that though. Looking through my cabinet, looks like 50mg B6 pryidoxine HCl (which seems high compared to another brand I looked up and a sibling comment). Not sure why I kept those, tossed it out now.

But I was really just wanting B1 and a bit more shopping found drops (annoying) and tablets with only B1 and negligble other stuff.