fwiw tirzepatide (likely the GIP component) cleared up my lifelong IBS within days of my first dose.

I consider it a likely lifelong medication now simply due to that night and day difference to my life. It’s extremely rare I have a day where I need to be within 5 minutes of a restroom now.

My primary care doctor mentioned this might be a side effect when I first started, and she ended up being more correct than even she expected to be.