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Re:Migraine is more than a headache – a rethink offers hope ... by xvedejas on Tuesday February 18, 2025 @10:20PM (#43098196)
Even sub-psychedelic doses of tryptamines is known to have an effect on certain migraines and cluster headaches: https://en.m.wikipedia.org/wiki/Triptan
Re:Migraine is more than a headache – a rethink offers hope ... by 3D30497420 on Wednesday February 19, 2025 @03:25AM (#43099886)
I take a triptan for mine (naratriptan) and it has helped. Certainly not a cure though.
Re:Migraine is more than a headache – a rethink offers hope ... by ulrikrasmussen on Wednesday February 19, 2025 @03:48AM (#43100024)
Can this family of drugs even give a psychedelic experience at higher doses? They are acting on 5-HT1B and 5-HT1D, not the 5-HT2A receptors that psychedelics act on.