The MFP of a 120 PeV neutrino in lead would be something like 10 kilometers, I think.
So BIG boom.
Since the velocity is so close to the speed of light, you can think of this like the energy released by annihilating a ping pong ball made of antimatter.
Edit: Commenter asked what would happen if they "hit", so I'm assuming a hypothetical 100% collision. But yes to stop 1/e of a neutrino beam with normal matter, you'd need a light year of lead.
The probability of interaction of neutrinos with matter increases with the energy. I've asked o1 to estimate the mean free path of a 120 PeV neutrino in water and it came up with 1000km. So let's say, conservatively, that 10^-7 of the total energy gets deposited in your body when the beam goes through. The mass equivalent of a ping pong ball is about 2.5x10^14 J, which gives us 2.5x10^7 J total, or about 6kg TNT equivalent. This is only an order-of-magnitude estimate, but it would definitely not be healthy.
From nothing, to detectable, to lethal, to big boom?
My intuition would be "detectable" but I don't know enough to do the maths.
And by the way, I am using the mass-energy, not proper mass, because the question is crazy enough not to even consider what would be the mass of a neutrino.