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Re:Ask HN: Breakthrough in Protein Folding by samsamlh on Sunday February 02, 2025 @11:11AM (#42909513)
Try to understand the maths, apply the circle / sphere transform and you’ll see that naturally it converges to a stable state. MD is the hard way, spherical transform is the easy way (nature uses it)

My theory on maths shows that any shape can have its points on a circle edge and midpoints on that same circle edge morphing showing all possible paths through radius scaling (P=C). It’s all about constraints.

Transforming the protein through 3D coordinates aligns all forces so it is fundamentally different than MD, it’s a geometric solver, so it is super fast!

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