I have a 4k projector setup which I use from time to time instead of my regular 27” monitor. It makes a pretty big difference especially as it is reflected light. I can sit in front of it for hours without any noticeable eye strain.

It’s fine for doing graphical work or web browsing but really not ideal for things like code or excel as I lose my place too often with my eyes having to dart around further. Might just be sitting too close though.