I think it's just a case of our ape bodies not being prepared for a modern world where calories are abundant - which is a good thing! It means people don't starve in developed countries.

We wear clothes because we evolved to not have hair. We wear glasses because we spend more time focusing on nearby objects. Some people need GLP-1 agonists because their body makes them consume food it doesn't need, and there's no scarcity to stop them. It's okay to use technology to adapt our bodies to a different world.