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Re:Francis Crick's "Central Dogma" was misunderstood by TeMPOraL on Sunday December 01, 2024 @09:47PM (#42292634)
That still makes no sense to me.

Same protein P is coded by two different sequences, A and B. The "redundancy" observation is just saying that when you find some P molecules in the organism, you can't tell which were coded by A and which by B - that information is, literally, lost in translation. Yes, it's not really lost - it's smeared over the "global state", as DNA sequences are physical objects and A and B have slightly different resource costs, but that's still far from being able to modify DNA based on information from proteins.

FWIW, "redundancy" does have some different interesting functions in nature. Sequences like "AAAA" "ABAB" and "BBBB" are (in this example) equivalent under normal read, but if you shift the reading window one nucleotide to the left or right, those two sequences could code for something else entirely. AFAIK some bacteria exploit that. But again, this is still not a protein->DNA information transfer.

Re:Francis Crick's "Central Dogma" was misunderstood by robwwilliams on Sunday December 01, 2024 @11:57PM (#42293246)
Nope. Do not forget tRNAs. Abundance and efficiency of production of proteins are also critical and that can depend on codon usage.