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Re:Psilocybin Bests SSRI for Major Depression in First Long-... by brandall10 on Saturday October 12, 2024 @02:51PM (#41821443)
Why did you take a very high dose?

As someone who was experienced with psilocybin some 20+ years ago, I always took fairly consistent doses (roughly 3 grams), as I could sense taking much more would be playing with fire. This was pretty much a given amongst my circle of a dozen friends who experienced these trips with me… hero doses were almost never a good or healthy idea. Fun to read about on Erowid though, mostly as cautionary tales.

My time with the substance ended after two bad trips (after a few dozen great ones over a period of 5 years), but neither produced any sort of even minor lasting effect.

Re:Psilocybin Bests SSRI for Major Depression in First Long-... by appplication on Saturday October 12, 2024 @03:10PM (#41821589)
> Why did you take a very high dose?

Hindsight is 20/20 but often it’s not clear at the time if it’s a bad idea or how bad it can be. I think it’s not such a fair question to someone struggling to find effective treatment for mental health issues to make a mistake on dosing. Especially given both government and medical field have historically not amenable to openly communicating harm reduction or safe guidelines for experimentation with this particular medicine.