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A comment on SARS-CoV-2-specific plasma cells not durably in bone marrow after mRNA vaccine.

Re:SARS-CoV-2-specific plasma cells not durably in bone marr... by eightysixfour on Tuesday October 01, 2024 @10:10AM (#41708688)
They say:

> In all, our studies suggest that rapid waning of SARS-CoV-2-specific serum antibodies could be accounted for by the absence of BM LLPCs after these mRNA vaccines.

But they also said:

> In five patients with known PCR-proven history of recent infection and vaccination, SARS-CoV-2-specific ASCs were mostly absent from the LLPCs.

Doesn’t that imply that all covid immunity, not just mRNA vaccines have this problem?

[ Parent | on HN ]
Re:SARS-CoV-2-specific plasma cells not durably in bone marr... by Cartoxy on Wednesday October 02, 2024 @12:59PM (#41722694)
Not necessarily. perhaps Initial mRNA immunity was not completely comprehensive. as in only offered partial immunity and reduced symptoms, maybe this alters the later immune system structure on repeat infection.
[ Parent | on HN ]