A lot of libraries seem to be working on Apple Silicon GPUs but not on ANE. I found this discussion interesting, seems like the ANE has a lot of limitations, is not well documented, and can only be used indirectly through Core ML. https://github.com/ggerganov/llama.cpp/discussions/336
This never made sense to me -- Apple could easily hire top talent to write Apple Silicon bindings for these popular libraries. I work at a creative ad agency, we have tons of high end apple devices yet the neural cores sit unused most of the time.